Researchers at Boston College have found that reducing calorie intake can restrict the growth and spread of one of the most aggressive and invasive forms of brain cancer.
The research group, led by Laura Shelton, reported success in tests on mice suffering from glioblastoma multiform, a serious form of primary human brain cancer.
Reporting in the current issue of ASN Neuro, the journal of the American Society for Neurochemistry, the researchers said restricting calorie intake lowers blood sugar levels and reduces the amount of carbohydrate energy available to the tumour cells, which rely heavily on glucose. Normal brain cells can use ketone carbons for energy.
The researchers say their findings “indicate that brain tumour cells are more sensitive to energy stress than normal brain cells and can be targeted through principles of metabolic control theory.”
They conclude that diets which lower glucose and elevate ketone levels — in other words, a low-carb diet — can be therapeutic for invasive brain tumours.
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Article by : QMI Agency